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Molecular Pathways: Context-dependent approaches to Notch targeting as cancer therapy

Recent high throughput genomic sequencing studies of solid tumors, including head and neck squamous cell carcinoma (SCC), ovarian cancer, lung adenocarcinoma, glioblastoma, breast cancer and lung SCC, have highlighted DNA mutation as a mechanism for aberrant Notch signaling. A primary challenge of t...

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Bibliografske podrobnosti
Main Authors: Egloff, Ann Marie, Grandis, Jennifer R.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463728/
https://ncbi.nlm.nih.gov/pubmed/22773520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2258
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