Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer

PURPOSE: A major factor limiting the effective clinical management of colorectal cancer (CRC) is resistance to chemotherapy. Therefore, the identification of novel, therapeutically targetable mediators of resistance is vital. EXPERIMENTAL DESIGN: We used a CRC disease-focused microarray platform to...

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Hlavní autoři: Stevenson, Leanne, Allen, Wendy L, Turkington, Richard, Jithesh, Puthen V, Proutski, Irina, Stewart, Gail, Lenz, Heinz-Josef, Schaeybroeck, Sandra Van, Longley, Daniel B, Johnston, Patrick G
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463501/
https://ncbi.nlm.nih.gov/pubmed/22859720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1780
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