UDP-glucose Dehydrogenase Polymorphisms from Patients with Congenital Heart Valve Defects Disrupt Enzyme Stability and Quaternary Assembly

Cardiac valve defects are a common congenital heart malformation and a significant clinical problem. Defining molecular factors in cardiac valve development has facilitated identification of underlying causes of valve malformation. Gene disruption in zebrafish revealed a critical role for UDP-glucos...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Hyde, Annastasia S., Farmer, Erin L., Easley, Katherine E., van Lammeren, Kristy, Christoffels, Vincent M., Barycki, Joseph J., Bakkers, Jeroen, Simpson, Melanie A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Glycobiology and Extracellular Matrices
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463334/
https://ncbi.nlm.nih.gov/pubmed/22815472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395202
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares