GATA2 Is a Critical Transactivator for the Human IL1RL1/ST2 Promoter in Mast Cells/Basophils: OPPOSING ROLES FOR GATA2 and GATA1 IN HUMAN IL1RL1/ST2 GENE EXPRESSION

The IL1RL1/ST2 gene encodes a receptor for IL-33. Signaling from IL1RL1/ST2 induced by IL-33 binding was recently identified as a modulator of the Th2 response. The target cells for IL-33 are restricted in some hematopoietic lineages, including mast cells, basophils, eosinophils, Th2 cells, natural...

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Detalhes bibliográficos
Main Authors: Baba, Yosuke, Maeda, Keiko, Yashiro, Takuya, Inage, Eisuke, Kasakura, Kazumi, Suzuki, Ryuyo, Niyonsaba, François, Hara, Mutsuko, Tanabe, Atsushi, Ogawa, Hideoki, Okumura, Ko, Ohtsuka, Yoshikazu, Shimizu, Toshiaki, Nishiyama, Chiharu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463314/
https://ncbi.nlm.nih.gov/pubmed/22865859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374876
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