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Cooperative Regulation of the Mucosal Mast Cell–Specific Protease Genes Mcpt1 and Mcpt2 by GATA and Smad Transcription Factors

Mouse mast cell proteases (mMCP)-1 and −2 are specifically expressed in mucosal mast cells (MCs). However, the transcriptional regulation mechanism of the Mcpt1 and Mcpt2 genes induced in mucosal MCs is largely unknown. In the current study, we found that TGF-β stimulation drastically induced upregu...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kasakura, Kazumi, Nagata, Kazuki, Miura, Ryosuke, Iida, Mayu, Nakaya, Hikaru, Okada, Hikaru, Arai, Takahiro, Kawakami, Yuko, Kawakami, Toshiaki, Yashiro, Takuya, Nishiyama, Chiharu
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219243/
https://ncbi.nlm.nih.gov/pubmed/32005755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900094
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