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Enzymatic Engineering of Polysialic Acid on Cells in Vitro and in Vivo Using a Purified Bacterial Polysialyltransferase

In vertebrates, polysialic acid (PSA) is typically added to the neural cell adhesion molecule (NCAM) in the Golgi by PST or STX polysialyltransferase. PSA promotes plasticity, and its enhanced expression by viral delivery of the PST or STX gene has been shown to promote cellular processes that are u...

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Hlavní autoři: El Maarouf, Abderrahman, Moyo-Lee Yaw, Damali, Lindhout, Theresa, Pearse, Damien D., Wakarchuk, Warren, Rutishauser, Urs
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463313/
https://ncbi.nlm.nih.gov/pubmed/22851175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377614
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