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Autopolysialylation of polysialyltransferases is required for polysialylation and polysialic acid chain elongation on select glycoprotein substrates

Polysialic acid (polySia) is a large glycan polymer that is added to some glycoproteins by two polysialyltransferases (polySTs), ST8Sia-II and ST8Sia-IV. As polySia modulates cell adhesion and signaling, immune cell function, and tumor metastasis, it is of interest to determine how the polySTs recog...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Bhide, Gaurang P., Zapater, Joseph L., Colley, Karen J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767873/
https://ncbi.nlm.nih.gov/pubmed/29183999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000401
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