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The Polysialyltransferases Interact with Sequences in Two Domains of the Neural Cell Adhesion Molecule to Allow Its Polysialylation

The neural cell adhesion molecule (NCAM) is the major substrate for the polysialyltransferases (polySTs), ST8SiaII/STX and ST8SiaIV/PST. The polysialylation of NCAM N-glycans decreases cell adhesion and alters signaling. Previous work demonstrated that the first fibronectin type III repeat (FN1) of...

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Hlavní autoři: Thompson, Matthew G., Foley, Deirdre A., Colley, Karen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591636/
https://ncbi.nlm.nih.gov/pubmed/23341449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.438374
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