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The Polysialyltransferases Interact with Sequences in Two Domains of the Neural Cell Adhesion Molecule to Allow Its Polysialylation

The neural cell adhesion molecule (NCAM) is the major substrate for the polysialyltransferases (polySTs), ST8SiaII/STX and ST8SiaIV/PST. The polysialylation of NCAM N-glycans decreases cell adhesion and alters signaling. Previous work demonstrated that the first fibronectin type III repeat (FN1) of...

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Библиографические подробности
Главные авторы: Thompson, Matthew G., Foley, Deirdre A., Colley, Karen J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591636/
https://ncbi.nlm.nih.gov/pubmed/23341449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.438374
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