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Sequences at the Interface of the Fifth Immunoglobulin Domain and First Fibronectin Type III Repeat of the Neural Cell Adhesion Molecule Are Critical for Its Polysialylation

Polysialic acid is an anti-adhesive glycan that modifies a select group of mammalian proteins. The primary substrate of the polysialyltransferases (polySTs) is the neural cell adhesion molecule (NCAM). Polysialic acid negatively regulates cell adhesion, is required for proper brain development, and...

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Bibliografiset tiedot
Päätekijät: Thompson, Matthew G., Foley, Deirdre A., Swartzentruber, Kristin G., Colley, Karen J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039361/
https://ncbi.nlm.nih.gov/pubmed/21131353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200386
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