The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling

During developmental and tumor angiogenesis, semaphorins regulate blood vessel navigation by signaling through plexin receptors that inhibit the R-Ras subfamily of small GTPases. R-Ras is mainly expressed in vascular cells, where it induces adhesion to the extracellular matrix (ECM) through unknown...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sandri, Chiara, Caccavari, Francesca, Valdembri, Donatella, Camillo, Chiara, Veltel, Stefan, Santambrogio, Martina, Lanzetti, Letizia, Bussolino, Federico, Ivaska, Johanna, Serini, Guido
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463263/
https://ncbi.nlm.nih.gov/pubmed/22825554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.110
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires