The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling

During developmental and tumor angiogenesis, semaphorins regulate blood vessel navigation by signaling through plexin receptors that inhibit the R-Ras subfamily of small GTPases. R-Ras is mainly expressed in vascular cells, where it induces adhesion to the extracellular matrix (ECM) through unknown...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sandri, Chiara, Caccavari, Francesca, Valdembri, Donatella, Camillo, Chiara, Veltel, Stefan, Santambrogio, Martina, Lanzetti, Letizia, Bussolino, Federico, Ivaska, Johanna, Serini, Guido
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2012
Θέματα:
Original Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463263/
https://ncbi.nlm.nih.gov/pubmed/22825554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.110
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