The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling

During developmental and tumor angiogenesis, semaphorins regulate blood vessel navigation by signaling through plexin receptors that inhibit the R-Ras subfamily of small GTPases. R-Ras is mainly expressed in vascular cells, where it induces adhesion to the extracellular matrix (ECM) through unknown...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sandri, Chiara, Caccavari, Francesca, Valdembri, Donatella, Camillo, Chiara, Veltel, Stefan, Santambrogio, Martina, Lanzetti, Letizia, Bussolino, Federico, Ivaska, Johanna, Serini, Guido
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2012
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463263/
https://ncbi.nlm.nih.gov/pubmed/22825554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.110
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