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Cloning, Expression, and Characterization of the Unique Bovine A(1) Adenosine Receptor: STUDIES ON THE LIGAND BINDING SITE BY SITE-DIRECTED MUTAGENESIS

The bovine brain A(1) adenosine receptor (A(1)AR) is distinct from other A(1)ARs in that it displays the unique agonist potency series of N(6)-R-phenylisopropyladenosine (R-PIA) > N(6)-S-phenylisopropyladenosine (S-PIA) > 5′-N-ethylcarboxamidoadenosinea nd has a 5–10-fold higher affinity for b...

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Bibliografiske detaljer
Main Authors: Olah, Mark E., Ren, Hongzu, Ostrowski, Jacek, Jacobson, Kenneth A., Stiles, Gary L.
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463104/
https://ncbi.nlm.nih.gov/pubmed/1587851
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