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TRIFUNCTIONAL LIGANDS: A RADIOIODINATED HIGH AFFINITY ACYLATING ANTAGONIST FOR THE A(1) ADENOSINE RECEPTOR

A new xanthine (adenosine antagonist) radioligand that binds covalently to A(1-)adenosine receptors was prepared and used as a receptor probe. BH-DITC-XAC was synthesized via a trifunctional aryl diisothiocyanate crosslinker. containing the p-hydroxyphenylpropionyl group for radioiodination. The xan...

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Detalhes bibliográficos
Principais autores: JACOBSON, KENNETH A., OLAH, MARK E., STILES, GARY L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217529/
https://ncbi.nlm.nih.gov/pubmed/25374448
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