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HIGH AFFINITY ACYLATING ANTAGONISTS FOR MUSCARINIC RECEPTORS

The muscarinic antagonists pirenzepine and telenzepine were derivitized as alkylamino derivatives at a site on the molecules corresponding to a region of bulk tolerance in receptor binding. The distal primary amino groups were coupled to the cross-linking reagent meta-phenylene diisothiocyanate, res...

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Detalhes bibliográficos
Main Authors: Baumgold, Jesse, Karton, Yishai, Malka, Naftali, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469257/
https://ncbi.nlm.nih.gov/pubmed/1625525
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