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Transcriptional Amplification in Tumor Cells with Elevated c-Myc
Elevated expression of the c-Myc transcription factor occurs frequently in human cancers and is associated with tumor aggression and poor clinical outcome. The effect of high levels of c-Myc on global gene regulation is poorly understood, but is widely thought to involve newly activated or repressed...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462372/ https://ncbi.nlm.nih.gov/pubmed/23021215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.026 |
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