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Transcriptional Amplification in Tumor Cells with Elevated c-Myc

Elevated expression of the c-Myc transcription factor occurs frequently in human cancers and is associated with tumor aggression and poor clinical outcome. The effect of high levels of c-Myc on global gene regulation is poorly understood, but is widely thought to involve newly activated or repressed...

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Bibliografische gegevens
Hoofdauteurs: Lin, Charles Y., Lovén, Jakob, Rahl, Peter B., Paranal, Ronald M., Burge, Christopher B., Bradner, James E., Lee, Tong Ihn, Young, Richard A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462372/
https://ncbi.nlm.nih.gov/pubmed/23021215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.026
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