Relationship between inflammation, bone destruction, and osteoproliferation in spondyloarthritis in HLA-B27/Huβ2m transgenic rats

OBJECTIVE: Inhibition of inflammation and destruction but not osteoproliferation in spondyloarthritis (SpA) patients treated with anti-TNF raises the question of how these three processes are interrelated. This study aimed to analyze this relationship in a SpA rat model. METHODS: Histological spine...

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Main Authors: van Duivenvoorde, Leonie M., Dorris, Martha L., Satumtira, Nimman, van Tok, Melissa N., Redlich, Kurt, Tak, Paul P., Taurog, Joel D., Baeten, Dominique L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462233/
https://ncbi.nlm.nih.gov/pubmed/22736144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34600
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