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For re-submission to Mutation Research, 7/30/07 Depletion of WRN Enhances DNA Damage in HeLa Cells Exposed to the Benzene Metabolite, Hydroquinone

Werner syndrome is a progeroid disorder caused by mutations of the WRN gene. The encoded WRN protein belongs to the family of RecQ helicases that plays a role in the maintenance of genomic stability. Single nucleotide polymorphisms in WRN have been associated with an increased risk for some cancers...

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Autors principals: Galván, Noé, Lim, Sophia, Zmugg, Stephan, Smith, Martyn T., Zhang, Luoping
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461953/
https://ncbi.nlm.nih.gov/pubmed/17875398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2007.07.011
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