WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells

BACKGROUND: The Werner syndrome protein (WRN) belongs to the RecQ family of helicases and its loss of function results in the premature aging disease Werner syndrome (WS). We previously demonstrated that an early cellular change induced by WRN depletion is a posttranscriptional decrease in the level...

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Bibliografiske detaljer
Udgivet i:BMC Mol Cell Biol
Main Authors: Iglesias-Pedraz, Juan Manuel, Fossatti-Jara, Diego Matia, Valle-Riestra-Felice, Valeria, Cruz-Visalaya, Sergio Rafael, Ayala Felix, Jose Antonio, Comai, Lucio
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557079/
https://ncbi.nlm.nih.gov/pubmed/33054770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00315-9
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