WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells

BACKGROUND: The Werner syndrome protein (WRN) belongs to the RecQ family of helicases and its loss of function results in the premature aging disease Werner syndrome (WS). We previously demonstrated that an early cellular change induced by WRN depletion is a posttranscriptional decrease in the level...

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Detaylı Bibliyografya
Yayımlandı:BMC Mol Cell Biol
Asıl Yazarlar: Iglesias-Pedraz, Juan Manuel, Fossatti-Jara, Diego Matia, Valle-Riestra-Felice, Valeria, Cruz-Visalaya, Sergio Rafael, Ayala Felix, Jose Antonio, Comai, Lucio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557079/
https://ncbi.nlm.nih.gov/pubmed/33054770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00315-9
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