The benzene metabolite, hydroquinone and etoposide both induce endoreduplication in human lymphoblastoid TK6 cells

Both occupational exposure to the leukemogen benzene and in vitro exposure to its metabolite hydroquinone (HQ) lead to the induction of numerical and structural chromosome changes. Several studies have shown that HQ can form DNA adducts, disrupt microtubule assembly and inhibit DNA topoisomerase II...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Ji, Zhiying, Zhang, Luoping, Guo, Weihong, McHale, Cliona M., Smith, Martyn T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Original Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701990/
https://ncbi.nlm.nih.gov/pubmed/19491217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gep018
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk