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Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling

The osteoporosis associated with human hyperthyroidism has traditionally been attributed to elevated thyroid hormone levels. There is evidence, however, that thyroid-stimulating hormone (TSH), which is low in most hyperthyroid states, directly affects the skeleton. Importantly, Tshr-knockout mice ar...

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Bibliografiske detaljer
Main Authors: Baliram, Ramkumarie, Sun, Li, Cao, Jay, Li, Jianhua, Latif, Rauf, Huber, Amanda K., Yuen, Tony, Blair, Harry C., Zaidi, Mone, Davies, Terry F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461920/
https://ncbi.nlm.nih.gov/pubmed/22996689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63948
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