Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling

The osteoporosis associated with human hyperthyroidism has traditionally been attributed to elevated thyroid hormone levels. There is evidence, however, that thyroid-stimulating hormone (TSH), which is low in most hyperthyroid states, directly affects the skeleton. Importantly, Tshr-knockout mice ar...

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Detalhes bibliográficos
Main Authors: Baliram, Ramkumarie, Sun, Li, Cao, Jay, Li, Jianhua, Latif, Rauf, Huber, Amanda K., Yuen, Tony, Blair, Harry C., Zaidi, Mone, Davies, Terry F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461920/
https://ncbi.nlm.nih.gov/pubmed/22996689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63948
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