Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling

The osteoporosis associated with human hyperthyroidism has traditionally been attributed to elevated thyroid hormone levels. There is evidence, however, that thyroid-stimulating hormone (TSH), which is low in most hyperthyroid states, directly affects the skeleton. Importantly, Tshr-knockout mice ar...

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Bibliographische Detailangaben
Hauptverfasser: Baliram, Ramkumarie, Sun, Li, Cao, Jay, Li, Jianhua, Latif, Rauf, Huber, Amanda K., Yuen, Tony, Blair, Harry C., Zaidi, Mone, Davies, Terry F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2012
Schlagworte:
Brief Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461920/
https://ncbi.nlm.nih.gov/pubmed/22996689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63948
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