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Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis
Intrinsic stress response pathways are frequently mobilized within tumor cells. The mediators of these adaptive mechanisms and how they contribute to carcinogenesis remain poorly understood. A striking example is heat shock factor 1 (HSF1), master transcriptional regulator of the heat shock response...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461912/ https://ncbi.nlm.nih.gov/pubmed/22945628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62727 |
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