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Suppressing T cell motility induced by anti–CTLA-4 monotherapy improves antitumor effects
A promising strategy for cancer immunotherapy is to disrupt key pathways regulating immune tolerance, such as cytotoxic T lymphocyte–associated protein 4 (CTLA-4). However, the determinants of response to anti–CTLA-4 mAb treatment remain incompletely understood. In murine models, anti–CTLA-4 mAbs al...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461908/ https://ncbi.nlm.nih.gov/pubmed/22945631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61931 |
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