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Invariant natural killer T cells regulate breast cancer response to radiation and CTLA-4 blockade

PURPOSE: Immunoregulatory and suppressive mechanisms represent major obstacles to the success of immunotherapy in cancer patients. We have shown that the combination of radiotherapy (RT) to the primary tumor and CTLA-4 blockade induces anti-tumor immunity inhibiting metastases and extending the surv...

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Detalhes bibliográficos
Main Authors: Pilones, Karsten A., Kawashima, Noriko, Yang, Anne Marie, Babb, James S., Formenti, Silvia C., Demaria, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730222/
https://ncbi.nlm.nih.gov/pubmed/19147765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1277
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