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Molecular pathogenesis of multiple myeloma and its premalignant precursor
Multiple myeloma is a monoclonal tumor of plasma cells, and its development is preceded by a premalignant tumor with which it shares genetic abnormalities, including universal dysregulation of the cyclin D/retinoblastoma (cyclin D/RB) pathway. A complex interaction with the BM microenvironment, char...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461901/ https://ncbi.nlm.nih.gov/pubmed/23023717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61188 |
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