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The molecular pathogenesis of multiple myeloma

Multiple Myeloma (MM) is characterized by uncontrolled proliferation and accumulation of clonal plasma cells within the bone marrow. However, the cell of origin is a B-lymphocyte acquiring aberrant genomic events in the germinal center of a lymph node as off-target events during somatichypermutation...

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Détails bibliographiques
Publié dans:Hematol Rep
Auteurs principaux: Bolli, Niccolò, Martinelli, Giovanni, Cerchione, Claudio
Format: Artigo
Langue:Inglês
Publié: PAGEPress Publications, Pavia, Italy 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7772755/
https://ncbi.nlm.nih.gov/pubmed/33408844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/hr.2020.9054
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