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Regulation of oncogene-induced cell cycle exit and senescence by chromatin modifiers

Oncogene activation leads to dramatic changes in numerous biological pathways controlling cellular division, and results in the initiation of a transcriptional program that promotes transformation. Conversely, it also triggers an irreversible cell cycle exit called cellular senescence, which allows...

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Autor principal: David, Gregory
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461821/
https://ncbi.nlm.nih.gov/pubmed/22825329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21116
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