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Regulation of oncogene-induced cell cycle exit and senescence by chromatin modifiers
Oncogene activation leads to dramatic changes in numerous biological pathways controlling cellular division, and results in the initiation of a transcriptional program that promotes transformation. Conversely, it also triggers an irreversible cell cycle exit called cellular senescence, which allows...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461821/ https://ncbi.nlm.nih.gov/pubmed/22825329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21116 |
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