Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells

Lignende værker

• Specific Targeting of MTAP-deleted Tumors with a Combination of 2′-Fluoroadenine and 5′-Methylthioadenosine
  af: Tang, Baiqing, et al.
  Udgivet: (2018)
• Expression of MTAP Inhibits Tumor-Related Phenotypes in HT1080 Cells via a Mechanism Unrelated to Its Enzymatic Function
  af: Tang, Baiqing, et al.
  Udgivet: (2014)
• Methylthioadenosine phosphorylase (MTAP)-deficient T-cell ALL xenografts are sensitive to pralatrexate and 6-thioguanine alone and in combination
  af: Tedeschi, Philip M., et al.
  Udgivet: (2015)
• Germline Mutations in Mtap Cooperate with Myc to Accelerate Tumorigenesis in Mice
  af: Kadariya, Yuwaraj, et al.
  Udgivet: (2013)
• Chemical Genetic Screening for Compounds that Preferentially Inhibit Growth of Methylthioadenosine Phosphorylase (MTAP) Deficient Saccharomyces Cerevisiae
  af: Kadariya, Yuwaraj, et al.
  Udgivet: (2010)