Inhibition of p38-MAPK alters SRC coactivation and estrogen receptor phosphorylation

The p38 mitogen activated protein kinase pathway (MAPK) is known to promote cell survival, endocrine therapy resistance and hormone independent breast cancer cell proliferation. Therefore, we utilized the novel p38 inhibitor RWJ67657 to investigate the relevance of targeting this pathway in the ER(+...

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Detalles Bibliográficos
Main Authors: Antoon, James W., Bratton, Melyssa R., Guillot, Lori M., Wadsworth, Scott, Salvo, Virgilio A., Burow, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2012
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461809/
https://ncbi.nlm.nih.gov/pubmed/22825349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20992
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