Rapid Estrogen-Induced Phosphorylation of the SRC-3 Coactivator Occurs in an Extranuclear Complex Containing Estrogen Receptor

SRC-3/AIB1/ACTR/pCIP/RAC3/TRAM1 is a primary transcriptional coregulator for estrogen receptor (ER). Six SRC-3 phosphorylation sites have been identified, and these can be induced by steroids, cytokines, and growth factors, involving multiple kinase signaling pathways. Using phosphospecific antibodi...

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Autori principali: Zheng, Fuzhong F., Wu, Ray-Chang, Smith, Carolyn L., O'Malley, Bert W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234335/
https://ncbi.nlm.nih.gov/pubmed/16135815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.8273-8284.2005
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