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Inhibition of p38-MAPK alters SRC coactivation and estrogen receptor phosphorylation
The p38 mitogen activated protein kinase pathway (MAPK) is known to promote cell survival, endocrine therapy resistance and hormone independent breast cancer cell proliferation. Therefore, we utilized the novel p38 inhibitor RWJ67657 to investigate the relevance of targeting this pathway in the ER(+...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461809/ https://ncbi.nlm.nih.gov/pubmed/22825349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20992 |
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