Increased β-Amyloid Deposition in Tg-SWDI Transgenic Mouse Brain Following In Vivo Lead Exposure

Previous studies in humans and animals have suggested a possible association between lead (Pb) exposure and the etiology of Alzheimer’s disease (AD). Animals acutely exposed to Pb display an over-expressed amyloid precursor protein (APP) and the ensuing accumulation of beta-amyloid (Aβ) in brain ext...

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Detalhes bibliográficos
Main Authors: Gu, Huiying, Robison, Gregory, Hong, Lan, Barrea, Raul, Wei, Xing, Farlow, Martin R., Pushkar, Yulia N, Du, Yansheng, Zheng, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461595/
https://ncbi.nlm.nih.gov/pubmed/22796588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2012.07.002
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