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The Unfolded Protein Response is activated in Connexin 50 mutant mouse lenses

The unfolded protein response is a set of cell signaling pathways recently recognized to be activated in the lens during both normal development and endoplasmic reticulum stress induced by either unfolded proteins or oxidative damage. While mutations in the gene for connexin 50 are known to cause au...

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Detalhes bibliográficos
Main Authors: Alapure, Bhagwat V., Stull, Jaime K., Firtina, Zeynep, Duncan, Melinda K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461258/
https://ncbi.nlm.nih.gov/pubmed/22713599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2012.06.004
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