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Abnormal Expression of Collagen IV in Lens Activates Unfolded Protein Response Resulting in Cataract
Human diseases caused by mutations in extracellular matrix genes are often associated with an increased risk of cataract and lens capsular rupture. However, the underlying mechanisms of cataract pathogenesis in these conditions are still unknown. Using two different mouse models, we show that the ac...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791016/ https://ncbi.nlm.nih.gov/pubmed/19858219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.060384 |
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