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Essential role of TAK1 in regulating mantle cell lymphoma survival

TGF-β–activated kinase 1 (TAK1), a member of the MAPK kinase family, plays a key role in B-cell growth and development. In the present study, we examined the potential role of TAK1 as a therapeutic target for lymphoma. Here, we show that the active phosphorylated form of TAK1 is abundantly expressed...

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Detalhes bibliográficos
Main Authors: Buglio, Daniela, Palakurthi, Sangeetha, Byth, Kate, Vega, Francisco, Toader, Dorin, Saeh, Jamal, Neelapu, Sattva S., Younes, Anas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460632/
https://ncbi.nlm.nih.gov/pubmed/22649101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-369397
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