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Annexin A2 and A5 Serve as New Ligands for C1q on Apoptotic Cells
C1q is the initiator of the classical complement pathway and opsonizes apoptotic cells to facilitate phagocytosis. Deficiency of C1q is the strongest known risk factor for development of systemic lupus erythematosus (SLE), which appears to be related to ensuing impaired clearance of apoptotic materi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460470/ https://ncbi.nlm.nih.gov/pubmed/22879587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341339 |
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