Annexin-II, DNA, and Histones Serve as Factor H Ligands on the Surface of Apoptotic Cells

Apoptotic cells are opsonized by complement components such as C1q and C3b, which increases their susceptibility to phagocytosis. Soluble complement inhibitors such as factor H (fH) also recognize apoptotic cells to minimize the pro-inflammatory effects of downstream complement activation. We used f...

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Detalhes bibliográficos
Main Authors: Leffler, Jonatan, Herbert, Andrew P., Norström, Eva, Schmidt, Christoph Q., Barlow, Paul N., Blom, Anna M., Martin, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823518/
https://ncbi.nlm.nih.gov/pubmed/19951950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045427
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