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Annexin A2 and A5 Serve as New Ligands for C1q on Apoptotic Cells

C1q is the initiator of the classical complement pathway and opsonizes apoptotic cells to facilitate phagocytosis. Deficiency of C1q is the strongest known risk factor for development of systemic lupus erythematosus (SLE), which appears to be related to ensuing impaired clearance of apoptotic materi...

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Autori principali: Martin, Myriam, Leffler, Jonatan, Blom, Anna M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460470/
https://ncbi.nlm.nih.gov/pubmed/22879587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341339
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