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Annexin-II, DNA, and Histones Serve as Factor H Ligands on the Surface of Apoptotic Cells
Apoptotic cells are opsonized by complement components such as C1q and C3b, which increases their susceptibility to phagocytosis. Soluble complement inhibitors such as factor H (fH) also recognize apoptotic cells to minimize the pro-inflammatory effects of downstream complement activation. We used f...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823518/ https://ncbi.nlm.nih.gov/pubmed/19951950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045427 |
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