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Determination of Ligand Pathways in Globins: APOLAR TUNNELS VERSUS POLAR GATES
Although molecular dynamics simulations suggest multiple interior pathways for O(2) entry into and exit from globins, most experiments indicate well defined single pathways. In 2001, we highlighted the effects of large-to-small amino acid replacements on rates for ligand entry and exit onto the thre...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460423/ https://ncbi.nlm.nih.gov/pubmed/22859299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.392258 |
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