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JAK Kinases in Health and Disease: An Update

Janus kinases (Jaks) are critical signaling elements for a large subset of cytokines. As a consequence they play pivotal roles in the patho-physiology of many diseases including neoplastic and autoimmune diseases. Small molecule Jak inhibitors as therapeutic agents have become a reality and the pale...

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Библиографические подробности
Главные авторы: Laurence, Arian, Pesu, Marko, Silvennoinen, Olli, O’Shea, John
Формат: Artigo
Язык:Inglês
Опубликовано: Bentham Open 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460320/
https://ncbi.nlm.nih.gov/pubmed/23028408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874312901206010232
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