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Therapeutic targeting of Janus kinases
Cytokines play pivotal roles in immunity and inflammation, and targeting cytokines and their receptors is an effective means of treating such disorders. Type I and II cytokine receptors associate with Janus family kinases (JAKs) to effect intracellular signaling. These structurally unique protein ki...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634846/ https://ncbi.nlm.nih.gov/pubmed/18613833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2008.00644.x |
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