Therapeutic targeting of Janus kinases

Cytokines play pivotal roles in immunity and inflammation, and targeting cytokines and their receptors is an effective means of treating such disorders. Type I and II cytokine receptors associate with Janus family kinases (JAKs) to effect intracellular signaling. These structurally unique protein ki...

Full description

Saved in:
Bibliographic Details
Main Authors: Pesu, Marko, Laurence, Arian, Kishore, Nandini, Zwillich, Sam, Chan, Gary, O’Shea, John J.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634846/
https://ncbi.nlm.nih.gov/pubmed/18613833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2008.00644.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items