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Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia
Abnormal replication timing has been observed in cancer but no study has comprehensively evaluated this misregulation. We generated genome-wide replication-timing profiles for pediatric leukemias from 17 patients and three cell lines, as well as normal B and T cells. Nonleukemic EBV-transformed lymp...
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Autores principales: | , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Cold Spring Harbor Laboratory Press
2012
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460179/ https://ncbi.nlm.nih.gov/pubmed/22628462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.138511.112 |
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