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Genome-Scale Analysis of Replication Timing: from Bench to Bioinformatics
Replication timing profiles are cell type-specific and reflect genome organization changes upon differentiation. In this protocol we describe how to analyze replication timing genome-wide in mammalian cells. Asynchronously cycling cells are pulse labeled with the nucleotide analog 5-bromo-2-deoxyuri...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111951/ https://ncbi.nlm.nih.gov/pubmed/21637205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.328 |
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