MGMT Inhibition Restores ERα Functional Sensitivity to Antiestrogen Therapy

Lignende værker

• MGMT inhibition in ER positive breast cancer leads to CDC2, TOP2A, AURKB, CDC20, KIF20A, Cyclin A2, Cyclin B2, Cyclin D1, ERα and Survivin inhibition and enhances response to temozolomide
  af: Bobustuc, George C., et al.
  Udgivet: (2018)
• Levetiracetam enhances p53-mediated MGMT inhibition and sensitizes glioblastoma cells to temozolomide
  af: Bobustuc, George C., et al.
  Udgivet: (2010)
• New insights into estrogenic regulation of O(6)-methylguanine DNA-methyltransferase (MGMT) in human breast cancer cells: Co-degradation of ER-α and MGMT proteins by fulvestrant or O(6)-benzylguanine indicates fresh avenues for therapy
  af: Paranjpe, Ameya, et al.
  Udgivet: (2016)
• CADD-50. AN OLD STORY (MGMT) IN AN EXPANDED CONTEXT (NATIONAL CANCER DATABASE)
  af: Konduri, Santhi, et al.
  Udgivet: (2018)
• Disulfiram is a direct and potent inhibitor of human O(6)-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage
  af: Paranjpe, Ameya, et al.
  Udgivet: (2014)