Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

The apolipoprotein E (APOE) genotype is the major genetic risk factor for Alzheimer's disease (AD). We have access to cerebrospinal fluid (CSF) and plasma APOE protein levels from 641 individuals and genome-wide genotyped data from 570 of these samples. The aim of this study was to test whether...

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Détails bibliographiques
Auteurs principaux: Cruchaga, Carlos, Kauwe, John S.K., Nowotny, Petra, Bales, Kelly, Pickering, Eve H., Mayo, Kevin, Bertelsen, Sarah, Hinrichs, Anthony, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Association Studies Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459471/
https://ncbi.nlm.nih.gov/pubmed/22821396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds296
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